Neurogenesis & Neural Plasticity Lab

Understanding how the brain is built, maintained, and reshaped across the lifespan.

The NeuroPlaNe Lab is based in the Department of Cell Biology, Functional Biology and Physical Anthropology at the Universitat de València. Our research focuses on how the brain is built, maintained, and remodeled from embryonic development through postnatal and adult life.

We investigate the cellular and developmental mechanisms underlying neurogenesis, prolonged neuronal maturation, and structural plasticity throughout life. In particular, we study how neural stem and progenitor cells generate neurons from embryonic stages to adulthood, how specific neuronal populations retain immature features over extended periods, and how these processes contribute to the progressive refinement and lifelong remodeling of neural circuits.

Our work combines developmental and postnatal neuroscience with comparative approaches across species to uncover fundamental principles governing brain maturation. By integrating cellular, structural, and functional perspectives, we aim to better understand how the timing and regulation of neuronal development shape brain function across the lifespan.

Ultimately, our research seeks to elucidate how alterations in these processes contribute to neurodevelopmental and neurological disorders, bridging basic and translational neuroscience to advance our understanding of brain plasticity in health and disease.