Universitat de València · Dept. de Biologia Cel·lular, Biologia Funcional i Antropologia Física
NeuroPlaNe Lab
NeuroPlaNe Lab
Neurogenesis & Neural Plasticity
Cellular & Developmental Neuroscience

How the brain is built, maintained, and reshaped across life.

We investigate how neural stem cells generate neurons, why some remain immature for years before joining circuits, and how these processes differ from rodents to humans — bridging basic and translational neuroscience.

Fig. 1Ventricular zone —progenitor dynamicsFig. 2Immature neurons —prolonged maturationFig. 3Paralaminar amygdala —across species
Coronal hemisection · schematicNeuroPlaNe Lab
Research programme

Three questions, from a single progenitor to a human circuit.

Fig. 1

Human brain development & progenitor dynamics

Ganglionic eminences · radial glia · migration

How cellular diversity emerges in the developing human forebrain, and why progenitor dynamics and migratory routes don't follow the rodent playbook.

Early disruptions seed neurodevelopmental disorders →
Fig. 2

Immature neurons & prolonged maturation

DCX+ populations · plasticity · vulnerability

Populations that stay partly differentiated for extended periods — a possible reservoir recruited later into existing circuits, and a window into how plasticity turns into vulnerability.

Linked to epilepsy & autism spectrum disorder →
Fig. 3

The paralaminar amygdala across species

Comparative · smooth vs folded brains

A defined system rich in late-maturing neurons. We ask whether comparable structures exist in mouse, ferret and pig, and how they vary between lissencephalic and gyrencephalic brains.

A model for emotional-circuit refinement →
Comparative approach

One question, read across the vertebrate brain.

Why do rodent findings so often fail to translate to humans? We answer comparatively — pairing molecular markers with high-resolution ultrastructure across species with very different brains. Select a specimen to filter the publications.

Latest news

What's happening in the lab.

People

A small team working at cellular resolution.

VH
Vicente Herranz Pérez
Principal Investigator
PG
Patricia García Tárraga
Lab Manager
RM
Raquel Morales Gallel
AECC PhD Student
RE
Rafael Esteve Pérez
GVA PhD Student
Open positions & stays

Curious about how neurons grow up?

We welcome motivated students and researchers in developmental neuroscience, comparative neuroanatomy and electron microscopy — Master's projects, PhD, and visiting stays.

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